|Biomedical research projects
Through highly integrated research, the UNC-CH SRP produces critical
information for improving the accuracy of risk assessment to reduce exposure to toxic
chemicals and protect human health. The center's biomedical research focuses on three major classes of chemicals - polycyclic aromatic hydrocarbons (PAHs), halogenated hydrocarbons, and heavy metals.
Biomedical research themes cross multiple projects and cores include:
To learn more about the biomedical research projects supported by the UNC-CH SRP click on one of the projects listed in the tool bar on the left.
- developing biomarkers of exposure and effect for human and experimental models of environmental disease over a range of exposure levels to improve low-dose quantitative risk assessment;
- applying new molecular tools in a systems biology framework to understand metabolic pathways critical for environmental disease;
- predict in vivo inter-individual differences in susceptibility and risk;
- using advanced analytical tools to identify mechanisms of genotoxicity; and,
- using advanced statistical and bioinformatics methods to evaluate gene-environment interactions.
This research is supported by a grant from the National Institute of Environmental Health Sciences (#P42ES005948).
Last updated January 29, 2013