Environmental Sciences and Engineering
Ivan Rusyn's Biosketch
Ivan Rusyn's website
Rusyn Laboratory Home Page
REACH NC (Collexis) Research Profile
|1994||Ukrainian State Medical University, Kiev, Ukraine||MD, Medicine|
|2000||University of North Carolina at Chapel Hill||PhD, Toxicology|
|ENVR442||Biochemical and Molecular Toxicology|
The research focus of my laboratory is to apply genomics approaches to understand the molecular mechanisms of chemical-induced carcinogenesis. Specifically, we are interested in nuclear receptor-mediated pathways, DNA damage and repair, and the role of diet in cancer. Through a combination of in vivo animal studies and experiments that utilize cellular and molecular models we aim to better understand why certain chemicals cause cancer in rodents and whether humans are at risk from similar exposures.
|Lonsdale J. et a; (2013)|
The Genotype-Tissue Expression (GTEx) project.
Nature Genetics: vol.45, p.580-585.
|Soldatow V. Y. et al. (2013)|
In vitro models for liver toxicity testing.
Toxicology Research: vol.2, p.23-39.
|Rusyn I. and Bataller, R. (2013)|
Journal of Hepatology
|Uehara T., et al. (2013)|
Molecular mechanisms of fibrosis-associated promotion of liver carcinogenesis.
Toxicological Sciences: vol.132, p.53-63.
|Rusyn I. and Pogribny I.P. (2013)|
Environmental toxicants, epigenetics, and cancer..
Advances in Experimnetal Medicine and Biology: vol.754, p.215-232.