|Research Assistant Professor (Retired)
|1984||University of North Carolina, Chapel Hill||PhD, Atmospheric Chemistry|
|1979||University of North Carolina, Chapel Hill||MSPH, Atmospheric Chemistry|
|1974||West Virginia University||BS, Chemistry|
My research activities include the atmospheric chemistry of urban systems of nitrogen oxides and hydrocarbons, with the focus on understanding the reactive chemistry producing ozone and other photochemical products, using smog chambers. Research includes producing data suitable for modeling and for the purposes of evaluating chemical mechanisms for use in air quality simulation models for ozone, secondary organic aerosols and air toxics. I have expanded efforts to developing new technological systems to interface smog chambers and in vitro toxicological exposure systems for evaluating the effects of photochemistry on urban air mixtures and the resulting toxic potential for health effects. These new toxicological systems include developing new in vitro exposure apparatus for particulate matter, and a new laboratory and outdoor chamber including both toxicology and analytical capabilities. Research results demonstrate the effects of different policy control scenarios (such as alternative fuels) and the relative toxicity of ozone and other secondary air pollutants, particulate matter, and air toxics, which help guide development of air quality models needed for risk assessment of multipollutant mixtures found in air.
|Sexton, Kenneth G., Jeffries, Harvey E., Jang, M. , Kamens, R. M. , Doyle, M. , Voicu, I. , Jaspers, I. (2004)|
Photochemical products in urban mixtures enhance inflammatory responses in lung cells.
Inhalation Toxicology: vol.16 Suppl 1, p.107-14.
|de Bruijne, K.; Ebersviller, S.; Sexton, K. G.; Lake, S.; Leith, D.; Goodman, R.; Jetters, J.; Walters, G. W.; Doyle-Eisele, M.; Woodside, R.; Jeffries, H. E., and Jaspers, I. (2009)|
Design and testing of Electrostatic Aerosol in Vitro Exposure System (EAVES): an alternative exposure system for particles.
Inhalation Toxicology: vol.21(2), p.91-101.
|Sexton, K. G.; Doyle, M.; Jeffries, H. E., and Ebersviller, S. (2007)|
Development and Testing of a Chemical Mechanism for Atmospheric Photochemical Transformations of 1,3-Butadiene..
Chemico-Biological Interactions: vol.166(1-3), p.156-162.
|Doyle, M., Sexton, K. G., Jeffries, H., Bridge, K., Jaspers, I. (2004)|
Effects of 1,3-butadiene, isoprene, and their photochemical degradation products on human lung cells.
Environ Health Perspect: vol.112, p.1488-95.
|Li, Y.; Gibson, J. M.; Jat, P.; Puggioni, G.; Hasan, M.; West, J. J.; Vizuete, W.; Sexton, K.; Serre, M. (2010)|
Burden of disease attributed to anthropogenic air pollution in the United Arab Emirates: estimates based on observed air quality data.
Sci Total Environ: vol.408, p.5784-93.